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Familial Breast Cancer

There are several genes involved in the development of hereditary breast cancer, which, if mutated, lead to a greatly increased risk of developing the disease. These are genes which normally control cell growth and prevent breast cells becoming cancerous.

Two well-known genes involved in familial breast cancer are BRCA1 and BRCA2 (from the abbreviation of ‘breast cancer 1’ and ‘breast cancer 2’). However, not all familial breast cancers can be explained by an inherited gene change in BRCA1 or BRCA2, suggesting the involvement of other, as yet undiscovered, genes.

Familial breast cancer research we fund investigates:

  • Identifying new genes that are involved in hereditary breast cancer.
  • Looking at new ways to determine those at high risk of developing familial breast cancer.
  • Continuing support for a tissue bank resource used specifically for research into familial breast cancer.