A novel breast cancer treatment with reduced side effects

Start Year: 2014
Finish Year: 2015
Chief Investigator: Dr Kristy Brown
Grant Type: Novel Concept Awards
Institution: Monash University

Seventy per cent of breast cancers are fuelled by the hormone oestrogen. A gut hormone, ghrelin, may hold the key to halting oestrogen production and tumour growth in breast tissue. Dr Kristy Brown has made the novel discovery that ghrelin blocks oestrogen production in breast fat cells and is now working to determine the precise mechanisms of action.

Dr Brown will use laboratory models of breast cancer to define potential drug treatments that can be used to halt oestrogen production and tumour growth. These studies are intended to provide the information that is needed to apply therapies to treat breast cancer patients.