Improving breast cancer outcomes through weight management

Start Year: 2013
Finish Year: 2016
Chief Investigator: Dr Marina Reeves
Grant Type: Early Career Fellowship
Institution: The University of Queensland

Early Career Fellowship

The prognosis for women with metastatic breast cancer is poor. The precise mechanisms of breast cancer spread are still unclear.

This study focuses on members of a cell protein family called BCL-2, which regulate apoptosis, a process of cell death that is frequently impaired in cancer cells.

Studies of various cancers have reported a link between expression of BCL-2 family members and patient outcome. This observation has led to the hypothesis that some of these proteins may be involved in the development and spread of breast cancer.

This research will help to better understand breast cancer progression and to design improved treatments.