Novel microRNA regulators in the breast cancer EMT

Start Year: 2010
Finish Year: 2013
Chief Investigator: Professor Erik Thompson
Grant Type: Cancer Australia Priority Driven Collaborative Cancer Research Scheme(PdCCRS)
Institution: University of Melbourne

Priority-driven Collaborative Cancer Research Scheme (PdCCRS)

Breast cancer cells undergo a transformation (EMT) which helps them escape from the primary tumour, spread to distant sites and resist current therapies. Evidence has shown that EMT is regulated by a new type of molecule called microRNAs.

This study aims to further characterise the role of these microRNAs in EMT and in breast cancer in general by studying model systems and clinical samples. These studies are designed to identify new diagnostic and therapeutic opportunities in breast cancer.

This research is co-funded by Cancer Australia.