Targeting of two aspects of metabolism for cancer therapy

Start Year: 2011
Finish Year: 2014
Chief Investigator: Dr Anneke Blackburn
Grant Type: Cancer Australia Priority Driven Collaborative Cancer Research Scheme(PdCCRS)
Institution: Australian National University

Priority-driven Collaborative Cancer Research Scheme (PdCCRS)

This project aims to develop a novel strategy for killing cancer cells. The metabolic balance of cancer cells can be upset by redirecting fuel molecules down one pathway with one drug and then blocking that pathway with a second drug effectively killing cancer cells with little toxicity to normal cells.

The investigators use drugs already in clinical use so that they may be adapted quickly for cancer treatment.

This research is co-funded by NBCF and Cancer Australia.