Breast cancer is a disease of the genes. Through the sequencing of the human genome, we now have a much greater understanding of breast cancer at the genetic level.
This has led to the discovery that breast cancer is, in fact, not one disease but many – there are up to ten different sub-types of breast cancer. Each sub-type develops, progresses and responds to treatment very differently. A greater understanding of the complexity of breast cancer has led to a more tailored, personalised approach to treatment – where the genetic ‘signature’ of a particular person’s breast cancer will be used to determine the most effective, targeted treatment options.
Personalising treatments research we fund investigates:
- Finding new approaches to overcome resistance to existing cancer medicine
- Identifying gene signatures that can help optimise breast cancer treatment
- Determining which patients would benefit from radiotherapy